Trine Krogh-Madsen, "Modeling and Simulating Cardiac Electrical Activity"
English | ISBN: 0750320621 | 2020 | 236 pages | PDF | 26 MB
This book provides a thorough introduction to the topic of mathematical modeling of electrical activity in the heart, from molecular details of ionic channel dynamics to clinically derived patient-specific models. It discusses how cellular ionic models are formulated, introduces commonly used models and explains why there are so many different models available. The chapters cover modeling of the intracellular calcium handling that underlies cellular contraction as well as modeling molecular-level details of cardiac ion channels, and specialized topics such as cardiomyocyte energetics and signalling pathways. It is an excellent resource for experienced and specialized researchers in the field, but also biological scientists with a limited background in mathematical modelling and computational methods.
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